听力与言语-语言病理学

行为科学

医学伦理学

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  • Bacterial Catabolism of Dimethylsulfoniopropionate (DMSP).

    abstract::Dimethylsulfoniopropionate (DMSP) is a metabolite produced primarily by marine phytoplankton and is the main precursor to the climatically important gas dimethylsulfide (DMS). DMS is released upon bacterial catabolism of DMSP, but it is not the only possible fate of DMSP sulfur. An alternative demethylation/demethiola...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00172

    authors: Reisch CR,Moran MA,Whitman WB

    更新日期:2011-08-12 00:00:00

  • Type IVB Secretion Systems of Legionella and Other Gram-Negative Bacteria.

    abstract::Type IV secretion systems (T4SSs) play a central role in the pathogenicity of many important pathogens, including Agrobacterium tumefaciens, Helicobacter pylori, and Legionella pneumophila. The T4SSs are related to bacterial conjugation systems, and are classified into two subgroups, type IVA (T4ASS) and type IVB (T4B...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00136

    authors: Nagai H,Kubori T

    更新日期:2011-06-27 00:00:00

  • Long term seasonal dynamics of synechococcus population structure in the gulf of aqaba, northern red sea.

    abstract::Spatial patterns of marine Synechococcus diversity across ocean domains have been reported on extensively. However, much less is known of seasonal and multiannual patterns of change in Synechococcus community composition. Here we report on the genotypic diversity of Synechococcus populations in the Gulf of Aqaba, Nort...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00131

    authors: Post AF,Penno S,Zandbank K,Paytan A,Huse SM,Welch DM

    更新日期:2011-06-20 00:00:00

  • Microbial communities and chemosynthesis in yellowstone lake sublacustrine hydrothermal vent waters.

    abstract::Five sublacustrine thermal spring locations from 1 to 109 m water depth in Yellowstone Lake were surveyed by 16S ribosomal RNA gene sequencing in relation to their chemical composition and dark CO(2) fixation rates. They harbor distinct chemosynthetic bacterial communities, depending on temperature (16-110°C) and elec...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00130

    authors: Yang T,Lyons S,Aguilar C,Cuhel R,Teske A

    更新日期:2011-06-13 00:00:00

  • Technologies and approaches to elucidate and model the virulence program of salmonella.

    abstract::Salmonella is a primary cause of enteric diseases in a variety of animals. During its evolution into a pathogenic bacterium, Salmonella acquired an elaborate regulatory network that responds to multiple environmental stimuli within host animals and integrates them resulting in fine regulation of the virulence program....

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00121

    authors: McDermott JE,Yoon H,Nakayasu ES,Metz TO,Hyduke DR,Kidwai AS,Palsson BO,Adkins JN,Heffron F

    更新日期:2011-06-02 00:00:00

  • Subversion of mucosal barrier polarity by pseudomonas aeruginosa.

    abstract::The lumenal surfaces of human body are lined by a monolayer of epithelia that together with mucus secreting cells and specialized immune cells form the mucosal barrier. This barrier is one of the most fundamental components of the innate immune system, protecting organisms from the vast environmental microbiota. The m...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00114

    authors: Engel J,Eran Y

    更新日期:2011-05-26 00:00:00

  • Cell viability and functionality of probiotic bacteria in dairy products.

    abstract::Probiotic bacteria, according to the definition adopted by the World Health Organization in 2002, are live microorganisms, which when administered in adequate amounts confer a health benefit to the host. Recent studies show that the same probiotic strain produced and/or preserved under different storage conditions, ma...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00070

    authors: Vinderola G,Binetti A,Burns P,Reinheimer J

    更新日期:2011-05-03 00:00:00

  • Salmonella Interaction with and Passage through the Intestinal Mucosa: Through the Lens of the Organism.

    abstract::Salmonella enterica serotypes are invasive enteric pathogens spread through fecal contamination of food and water sources, and represent a constant public health threat around the world. The symptoms associated with salmonellosis and typhoid disease are largely due to the host response to invading Salmonella, and to t...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00088

    authors: Hallstrom K,McCormick BA

    更新日期:2011-04-29 00:00:00

  • Anchors for effectors: subversion of phosphoinositide lipids by legionella.

    abstract::The facultative intracellular pathogen Legionella pneumophila replicates in free-living amoebae and macrophages within a distinct compartment, the "Legionella-containing vacuole" (LCV). LCV formation involves phosphoinositide (PI) glycerolipids, which are key factors controlling vesicle trafficking pathways and membra...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00091

    authors: Hilbi H,Weber S,Finsel I

    更新日期:2011-04-27 00:00:00

  • An Extracellular Tetrathionate Hydrolase from the Thermoacidophilic Archaeon Acidianus Ambivalens with an Activity Optimum at pH 1.

    abstract:BACKGROUND:The thermoacidophilic and chemolithotrophic archaeon Acidianus ambivalens is routinely grown with sulfur and CO(2)-enriched air. We had described a membrane-bound, tetrathionate (TT) forming thiosulfate:quinone oxidoreductase. Here we describe the first TT hydrolase (TTH) from Archaea. RESULTS:A. ambivalens...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00068

    authors: Protze J,Müller F,Lauber K,Naß B,Mentele R,Lottspeich F,Kletzin A

    更新日期:2011-04-25 00:00:00

  • Lipopolysaccharide-Deficient Brucella Variants Arise Spontaneously during Infection.

    abstract::Lipopolysaccharide-deficient mutants of smooth Brucella species (rough mutants) have been shown to arise spontaneously in culture. However, in situ analysis of Brucella infected macrophages using antibody directed against O-polysaccharide suggested a loss of reactivity of Brucella consistent with the appearance of rou...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00054

    authors: Turse JE,Pei J,Ficht TA

    更新日期:2011-03-23 00:00:00

  • The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans.

    abstract::Plant defensins are active against plant and human pathogenic fungi (such as Candida albicans) and baker's yeast. However, they are non-toxic to human cells, providing a possible source for treatment of fungal infections. In this study, we characterized the mode of action of the antifungal plant defensin HsAFP1 from c...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00047

    authors: Aerts AM,Bammens L,Govaert G,Carmona-Gutierrez D,Madeo F,Cammue BP,Thevissen K

    更新日期:2011-03-16 00:00:00

  • Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis.

    abstract::Trachomatous trichiasis (TT) caused by repeated or chronic ocular infection with Chlamydia trachomatis is the result of a pro-fibrotic ocular immune response. At the conjunctiva, the increased expression of both inflammatory (IL1B, TNF) and regulatory cytokines (IL10) have been associated with adverse clinical outcome...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00010

    authors: Gall A,Horowitz A,Joof H,Natividad A,Tetteh K,Riley E,Bailey RL,Mabey DC,Holland MJ

    更新日期:2011-02-10 00:00:00

  • Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasome.

    abstract::Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes phagosomal degradation, and replicates in the macrophage cytosol. The macrophage uses a series of pattern recognition receptors to detect c...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2011.00016

    authors: Jones JW,Broz P,Monack DM

    更新日期:2011-02-03 00:00:00

  • The francisella tularensis proteome and its recognition by antibodies.

    abstract::Francisella tularensis is the causative agent of a spectrum of diseases collectively known as tularemia. The extreme virulence of the pathogen in humans, combined with the low infectious dose and the ease of dissemination by aerosol have led to concerns about its abuse as a bioweapon. Until recently, nothing was known...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2010.00143

    authors: Kilmury SL,Twine SM

    更新日期:2011-01-07 00:00:00

  • Evaluation of surrogate animal models of melioidosis.

    abstract::Burkholderia pseudomallei is the Gram-negative bacterial pathogen responsible for the disease melioidosis. B. pseudomallei establishes disease in susceptible individuals through multiple routes of infection, all of which may proceed to a septicemic disease associated with a high mortality rate. B. pseudomallei opportu...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2010.00141

    authors: Warawa JM

    更新日期:2010-12-29 00:00:00

  • Relationships between Cytokine Profiles and Signaling Pathways (IκB Kinase and p38 MAPK) in Parainfluenza Virus-Infected Lung Fibroblasts.

    abstract::Respiratory viruses such as parainfluenza virus (PIV) in individuals with certain genetic predispositions in early life are associated with the induction of wheezing, which can progress to the development of asthma. It has been suggested that aberrant production of various cytokines due to viral infection are associat...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2010.00124

    authors: Yoshizumi M,Kimura H,Okayama Y,Nishina A,Noda M,Tsukagoshi H,Kozawa K,Kurabayashi M

    更新日期:2010-11-15 00:00:00

  • Model systems to study plague pathogenesis and develop new therapeutics.

    abstract::The Gram negative bacterium Yersinia pestis can infect humans by multiple routes to cause plague. Three plague pandemics have occurred and Y. pestis has been linked to biowarfare in the past. The continued risk of plague as a bioweapon has prompted increased research to understand Y. pestis pathogenesis and develop ne...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2010.00119

    authors: Lawrenz MB

    更新日期:2010-11-04 00:00:00

  • Mammalian MicroRNAs: Post-Transcriptional Gene Regulation in RNA Virus Infection and Therapeutic Applications.

    abstract::RNA silencing mediated by microRNAs (miRNAs) is a recently discovered gene regulatory mechanism involved in various aspects of biology, such as development, cell differentiation and proliferation, and innate immunity against viral infections. miRNAs, which are a class of small (21-25 nucleotides) RNAs, target messenge...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2010.00108

    authors: Tsunetsugu-Yokota Y,Yamamoto T

    更新日期:2010-10-13 00:00:00

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